As Vic reunites with his old partner, Joe Clark, they try to settle what caused Joe to be kicked off the force. Meanwhile, Claudette and Dutch investigate the disappearance of a girl whose severed arm they found. Danny Sofer starts dealing with the results of her shooting Zayed Al-Thani.
- Michael Chiklis as Detective Vic Mackey
- Catherine Dent as Officer Danny Sofer
- Walton Goggins as Detective Shane Vendrell
- Michael Jace as Officer Julien Lowe
- Kenneth Johnson as Detective Curtis Lemansky
- Jay Karnes as Detective Dutch Wagenbach
- Benito Martinez as Captain David Aceveda
- and CCH Pounder as Detective Claudette Wyms
- Carl Weathers as Joe Clark
- Lucinda Jenney as Lanie Kellis
- Mark Rolston as Gordie Liman
- Melanie Lynskey as Marcy Lindhoff
- Cathy Cahlin Ryan as Corrine Mackey
- David Rees Snell as Detective Ronnie Gardocki
- Ronreaco Lee as Taylor Orrs
- Marc Vann as Bob Lindhoff
- Garland Whitt as Fleetwood Walker
- Matt Corboy as Officer Ray Carlson
- Susan Santiago as Veronica
- Donielle Artese as Latonya
- Anje Cornell as Homeless Guy
- Autumn Chiklis as Cassidy Mackey
- Joel Rosenthal as Matthew Mackey
- Ernie Sanchez as Pedro
- Colleen Kane as M.E.
- Guillermo Cespedes as Nurse
- "Breakdown" by Tantric
- "The Whole Truth" by Michael Penn
The title refers to the relationship between police partners. While Vic Mackey reunites with his old partner, his relationship with his current partner, Shane, is still fractured. Also, Dutch and Claudette disagree in their case, while Danny and Julien's partnership is put to test.
- International airdates:
- Germany: February 18, 2006
- France: August 16, 2007
- After examining a severed arm, Detective Dutch Wagenbach calls the act "domination and control Dr. Mengele experiments", in reference to Josef Mengele, a German physician that did numerous brutal experiments in Jews during World War II.
- Fleetwood Walker drives a 2002 Chevrolet Avalanche with a "FLTWD1" license plate.