As Vic and the Strike Team assimilate the fact that there's a price on their heads, they investigate a mass murder on a shelter for abused women. This causes Connie to get more involved than she expected. Also, the tension between Danny and Yassirah Al-Thani continues to escalate.
- Michael Chiklis as Detective Vic Mackey
- Catherine Dent as Officer Danny Sofer
- Walton Goggins as Detective Shane Vendrell
- Michael Jace as Officer Julien Lowe
- Kenneth Johnson as Detective Curtis Lemansky
- Jay Karnes as Detective Dutch Wagenbach
- Benito Martinez as Captain David Aceveda
- and CCH Pounder as Detective Claudette Wyms
- Jamie Brown as Connie Riesler
- Marguerite MacIntyre as Emma Prince
- Mark Rolston as Gordie Liman
- Matthew Glave as Mike Holden
- Cathy Cahlin Ryan as Corrine Mackey
- David Rees Snell as Detective Ronnie Gardocki
- Matthew John Armstrong as Officer Lou
- Veena Bidasha as Yassirah Al-Thani
- Corey Pearson as Bello
- Jon Huertas as Detective Robbie Villanueva
- Matt Corboy as Officer Ray Carlson
- Shawn Woods as Tecks
- Marc Goldsmith as Detective Branning
- Avner Garbi as Mr. Camaril
- Cody Arens as Mike Holden, Jr.
- Shawn H. Smith as Gerard
- Diana Yanez as Anita
- Elizabeth Janas as Dorea Pinchuk
"Homewrecker" is a slang term for someone that makes an effort to ruin someone else's life. This could refer to firefighter Mike Holden, who murders his wife and kidnaps their son in an attack of rage. It could also refer to Yassirah Al-Thani's efforts to ruin Officer Danny Sofer's career and life, after she killed her husband.
- International airdates:
- Germany: March 11, 2006
- France: August 29, 2007
- When Officer Danny Sofer asks Shane Vendrell if they're considering a female to join the Strike Team, Shane tells her sarcastically that they will bring "Batgirl and Charlie's Angels".
- This is the third appearance of the Strike Team's trademark presentation card. Vic Mackey gives it to Tecks so he could contact him.
- Tecks: Man, I never put my hand on any of my employees! That's some old school bullshit. They can't go down if their lips are busted up.
- Vic Mackey: You call me if you hear from Dorea and I don't haul the rest of your stable in... They can't go down if they're locked up.